アブストラクト（56巻2号：神奈川歯学）

神奈川歯学

Japanese

Title　： 近赤外線口腔内照射による大脳皮質賦活化の検討 - 唾液分泌量との関連 -
Subtitle　： 原著
Authors　： 坂口和歌子1), 大塚剛郎2), 渕田慎也3), 猿田樹理3), 槻木恵一1)*
Authors（kana）　：
Organization　： 1)神奈川歯科大学病理・組織形態学講座環境病理学分野, 2)神奈川歯科大学歯学部, 3)神奈川歯科大学教育企画部, *主任
Journal　： 神奈川歯学
Volume　： 56
Number　： 2
Page　： 125-132
Year/Month　： 2021 / 12
Article　： 原著
Publisher　： 神奈川歯科大学学会
Abstract　： 「緒言」 可視波長域に対し, 波長の長い領域を赤外線波長域といい, 赤外線は波長域により, 近赤外線, 中赤外線, 遠赤外線に分類されている. 近赤外線は700-2,500nm, 中赤外線は3,000-4,000nm, 遠赤外線は4,000-10,000,000nmとされている. 近赤外線は食料品や医薬品の非破壊検査, 近赤外線カメラによるセキュリティーや生体内物質を可視化するバイオイメージング, テレビやエア・コンディショナーのリモコンなど生物学, 医学, 薬学だけでなく我々の生活に至るまで様々な分野で活用されている. 近赤外線はヒトの体内を通り, ヘモグロビンにより吸収され, 酸素と結合した酸化ヘモグロビン(OXHb)と結合していない脱酸化ヘモグロビン(DXHb)では吸収のされ方が波長に応じて異なる. 医療の分野で使用されているパルスオキシメータは近赤外線を用いており, 指を通過する近赤外線を捉えて, 動脈血の酸素飽和度を測定している.
Practice　： 歯科学
Keywords　： 近赤外線, Near-infrared spectroscopy (NIRS), 口腔乾燥, 大脳皮質

English

Title　： Cerebral Cortex Activation by Near-Infrared Oral Irradiation
Subtitle　：
Authors　： Wakako SAKAGUCHI1), Takero OTSUKA2), Shinya FUCHIDA3), Juri SARUTA3), Keiichi TSUKINOKI1)
Authors（kana）　：
Organization　： 1)Department of Environmental Pathology, Kanagawa Dental University, 2)Department of Dentistry, Kanagawa Dental University, 3)Department of Education Planning, Kanagawa Dental University
Journal　： Kanagawa Shigaku
Volume　： 56
Number　： 2
Page　： 125-132
Year/Month　： 2021 / 12
Article　： Original article
Publisher　： Kanagawa Odontological Society
Abstract　： [Abstract] Near-infrared light, which has a shorter wavelength than far-infrared light, is used in a variety of fields from daily life to medicine. Near-infrared spectroscopy (NIRS) is a simple and non-invasive technique to view the activation reactivity of the cortical network. NIRS supports psychological and mental functions by measuring hemoglobin around the cerebral cortex under the head with near-infrared light. The right hemisphere of the cerebral cortex is associated with intuitive understanding, computational ability, and many other cognitive functions, while the left hemisphere is associated with motor and sensory perception and language comprehension. In this study, we measured brain activity using NIRS and experimentally verified whether brain activity is accelerated by irradiating the muscles around the oral cavity with a device that uses near-infrared light. We also compared the change in saliva volume before and after the irradiation. We found that irradiating the oral cavity with near-infrared light significantly increased the cerebral cortical blood flow and cerebral oxygen saturation level (n=11, p<0.05). Furthermore, when the amount of saliva before and after the experiment was compared, it was found that the amount of saliva increased after irradiation. These results suggest that irradiating the oral cavity with near-infrared radiation improves blood flow in the muscles around the oral cavity, activates the cerebral cortex, and affects the salivary glands. This result was thought to be due to the activity of the brain's neural activity and the corresponding increase in the local blood flow and blood volume in the brain. It was suggested that the continuation of such functional oral care may lead to factors that prolong healthy life.
Practice　： Dentistry
Keywords　： Near-infrared spectroscopy (NIRS)