アブストラクト（53巻1/2号：神奈川歯学）

神奈川歯学

English

Title　： Effects of Bone Formation deriving biosilanes
Subtitle　： Mini Review
Authors　： Katsura OHASHI, Kaori MIYAKE-AOKI, Yuka KAMEYAMA, Yuuki WADA, Tomotaro NIHEI
Authors（kana）　：
Organization　： Division of Clinical Biomaterials, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University
Journal　： Kanagawa Shigaku
Volume　： 53
Number　： 1/2
Page　： 52-53
Year/Month　： 2018 / 12
Article　： Report
Publisher　： Kanagawa Odontological Society
Abstract　： [Abstract] The aim of this study was to construct the material surface that allows cells to be compatible with it without their destruction by silane coupling agents having amide group (biosilanes). These biosilanes were expected to make a soft landing to cytoplasm through the hydrogen bonding between their amide groups and cells. Evaluations of cell affinity using glass substrates modified with the synthesized biosilanes revealed that many cells remain on the modified glass plate. In addition, the implantation into the body of immunodeficient mouse of a composite material composed of porous hydroxyapatite and osteoblast showed the formation of a bone-like structure.
Practice　： Dentistry
Keywords　： Biosilane, Cell affinity, Surface modification