アブストラクト（34巻2号：The Bulletin of Kanagawa Dental College）

The Bulletin of Kanagawa Dental College

English

Title　： Antifungal Effects of Incorporating Apatite Coated TiO2 Photocatalyst into Acrylic Resin
Subtitle　： Selective Proceedings of 40th General Meeting of Kanagawa Odontological Society, 2005
Authors　： Takeshi Shibata1, Kinya Tanaka1, Tomofumi Sawada1, Tota Shimizu1, Noriyuki Hosh1, Katsuhiko Kimoto1, Tomoji Sawada1, Akira Watazu1, Toru Nonami1, Minoru Toyoda1, Hidefumi Kumada2, Nobushiro Hamada2, Toshio Umemoto2
Authors（kana）　：
Organization　： 1Department of Oral and Maxillofacial Rehabilitation, 2Department of Infection Control, Kanagawa Dental College
Journal　： The Bulletin of Kanagawa Dental College
Volume　： 34
Number　： 2
Page　： 121-123
Year/Month　： 2006 / 9
Article　： Report
Publisher　： Kanagawa Odontological Society
Abstract　： The purpose of the present study was to develop an acrylic resin with antifungal and antifouling functions to absorb and decompose the debris, such as denture plaque, adhering to denture surfaces by utilizing the photocatalytic activity of apatite coated titanium dioxide (Ap-TiO2). In this paper, we report the results of our study on the antifungal effects of the acrylic resin. The specimen plates were randomly divided into four groups (n=3) as follows: 1) acrylic resin control (Co); 2) acrylic resin containing 1% Ap-TiO2; 3) acrylic resin contaning 5% Ap-TiO2; 4) acrylic resin containing 10% Ap-TiO2. Candida albicans ATCC 1002 was used to assay the antifungal effects of the specimen plates under Ultraviolet A (UVA) with black light source. There was a statistically significant decrease in all the 5% Ap-TiO2 specimens irradiated for 2, 4 and 6 hours (p<0.01) and in the 10% Ap-TiO2 specimens irradiated for 2 and 4 hours (p<0.01) when compared with the control. However, in clinical use, compounding excessive amounts of Ap-TiO2 must be avoided because of its detrimental influence on the mechanical properties and esthetics of the compounded resin. The results of the present study suggest that optimal antifungal effects on C. albicans occur at a compounding concentration of 5% Ap-TiO2 and an irradiation time of 4 hours minimum.
Practice　： Dentistry
Keywords　： Titanium dioxide(TiO2), Apatite, Acrlic resin, Candida albicans, Antifungal effect